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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNH6
All Species:
24.24
Human Site:
T74
Identified Species:
59.26
UniProt:
Q9H252
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H252
NP_110406.1
994
109925
T74
D
F
L
T
G
P
N
T
P
S
S
A
V
S
R
Chimpanzee
Pan troglodytes
XP_525954
1196
134979
T74
D
F
L
H
G
P
E
T
K
R
H
D
I
A
Q
Rhesus Macaque
Macaca mulatta
XP_001116131
994
109992
T74
D
F
L
T
G
P
N
T
P
S
S
A
V
S
R
Dog
Lupus familis
XP_853319
957
106637
T74
D
F
L
T
G
P
N
T
P
R
S
A
M
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER47
1195
135008
T74
D
F
L
H
G
P
E
T
K
R
H
D
I
A
Q
Rat
Rattus norvegicus
O54853
950
105687
T74
D
F
L
T
G
P
N
T
P
S
S
A
V
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511873
1200
135504
T74
D
F
L
H
G
P
E
T
K
R
H
D
I
A
Q
Chicken
Gallus gallus
Q9PT84
526
59775
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688778
1181
131984
T74
D
F
L
H
G
Q
L
T
K
R
H
A
I
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02280
1174
126352
E76
V
C
G
F
M
Y
G
E
L
T
D
K
E
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.2
97.5
86.8
N.A.
52.8
86.2
N.A.
52.6
47.3
N.A.
51.5
N.A.
33.6
N.A.
N.A.
N.A.
Protein Similarity:
100
64.1
98.7
88.8
N.A.
63.2
88.5
N.A.
63.6
50.5
N.A.
61.4
N.A.
49.8
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
86.6
N.A.
40
100
N.A.
40
0
N.A.
40
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
93.3
N.A.
60
100
N.A.
60
0
N.A.
60
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
50
0
40
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
0
0
0
0
0
0
0
0
0
10
30
0
0
0
% D
% Glu:
0
0
0
0
0
0
30
10
0
0
0
0
10
0
0
% E
% Phe:
0
80
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
80
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
40
0
0
0
0
0
0
40
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
40
0
0
10
0
0
0
% K
% Leu:
0
0
80
0
0
0
10
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
70
0
0
40
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
40
% Q
% Arg:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
40
% R
% Ser:
0
0
0
0
0
0
0
0
0
30
40
0
0
40
0
% S
% Thr:
0
0
0
40
0
0
0
80
0
10
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
30
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _